The Fit 4 Start Graduation Night, held at Luxexpo The Box alongside the Nexus Luxembourg 2025 event, celebrated the successful graduation of 15 startups from the 15th edition of Luxembourg’s flagship acceleration programme, managed by Luxinnovation.
Jean-Michel Gaudron
Following a competitive selection and pitching process in autumn 2024, 20 startups were selected for participation in Fit 4 Start from 420 applications submitted by companies from nearly 70 different countries. This 15th edition supported projects across three categories: digital, healthtech and space.
The startups received six months of tailored coaching, as well as a grant of €50,000 each – subject to incorporation in Luxembourg – provided by the Ministry of the Economy. Those that go on to raise additional funding and hire at least two employees may be eligible for a further €100,000 in public support.
Fit 4 Start plays a pivotal role at the core of Luxembourg’s national innovation ecosystem. Lex Delles, Minister of the Economy, SMEs, Energy and Tourism
“The 15 startups completing this edition of Fit 4 Start are a shining example of the excellence, diversity and potential of the young companies we support,” comments Mario Grotz, CEO of Luxinnovation. “Excellence, because they meet the highest standards in both technological innovation and entrepreneurial discipline. Diversity, because they represent a broad range of sectors – from digital health and AI to cybersecurity and sustainable technologies – and come from a wide array of international backgrounds. And potential, because they demonstrate strong prospects for growth, investment and real-world market impact.”
Launched ten years ago by the Ministry of the Economy, the Fit 4 Start acceleration programme is run by Luxinnovation in partnership with Technoport, the Luxembourg Space Agency (LSA), the Luxembourg City Incubator, the Luxembourg House of Financial Technology (LHoFT), the House of Biohealth, the Luxembourg House of Cybersecurity and LuxProvide. Since its inception, the programme has received over 3,000 applications from around the globe.
“Since 2015, Fit 4 Start has established itself as a cornerstone of Luxembourg’s innovation ecosystem and a benchmark programme internationally,” says Mickael Borger, Advisor – Start-Up Relations at Luxinnovation. “It offers real added value to entrepreneurs by providing a demanding and structured framework, based on clear performance and impact criteria, targeted coaching by leading experts, and a powerful springboard for growth – including increased visibility, strategic networking and privileged access to investors and industry partners.”
The 15 startups completing this edition of Fit 4 Start are a shining example of the excellence, diversity and potential of the young companies we support. Mario Grotz, CEO of Luxinnovation
Across 15 editions, nearly 200 startups from 35 countries have been supported. Beyond intensive coaching, Fit 4 Start has helped build a tight-knit, international entrepreneurial community over the past decade.
“Fit 4 Start plays a pivotal role at the core of Luxembourg’s national innovation ecosystem,” says Lex Delles, Minister of the Economy, SMEs, Energy and Tourism. “It helps attract cutting-edge companies from around the world while acting as a genuine springboard for young tech ventures — fully aligned with our ambition to enhance Luxembourg’s appeal. The programme embodies the spirit of the 10-point action plan we unveiled together with the Minister of Finance last March, by providing tailored support, facilitating access to funding and creating the right conditions for innovative solutions to emerge. It contributes to positioning Luxembourg as a leading innovation hub in Europe.”
To further strengthen ties and build on collective experience, the Fit 4 Start Alumni Club has been relaunched and is now open to all former participants. “This initiative will foster synergies and cross-collaboration. It is a strategic lever to boost innovation, support the international growth of startups and enhance Luxembourg’s standing as a European technology hub,” says Martin Guérin, Senior Advisor – Start-Up Relations at Luxinnovation.
At the close of the ceremony, applications officially opened for Fit 4 Start #16. The call will close at noon on 11 August 2025. As in previous editions, 20 startups will be selected across three categories: digital, health technologies and space. The final selection of participants will be announced in October during the Luxembourg Venture Days, after two days of pitches by the shortlisted candidates.
Digital ventures
Algora Luxembourg – www.algora.lu/ | Financial market intelligence platform that empowers investment professionals to manage and analyse financial research. |
DataSecure Anti-Ransomware Luxembourg – datasecure.ai/ | Cybersecurity solution based on AI-powered advanced algorithms to protect businesses against ransomware attacks. |
Elora Call Luxembourg – www.elora.lu/ | Platform for businesses to create their own Gen AI Helpdesk in less than an hour. |
Essembl Luxembourg | AI fashion advisor that helps users choose outfits, provides styling tips, and offers smart shopping advice based on their preferences. |
Kyomei Luxembourg – https://kyomei.ai/ | The most private AI assistant for psychotherapists Effortlessly generation of session notes, reports, and managing patients — all with uncompromising data privacy. |
LetzTrail Luxembourg – www.letztrail.com/ | Connecting trails, friends, and local businesses for a great outdoor experience. |
Partao Luxembourg – https://partao.com/ | Marketplace for spare parts for tractors and other construction equipment. |
Social Cooling Luxembourg – www.social-cooling.com/ | Helping businesses and governments cool their offices and workspaces with a plug-and-play air conditioner. |
HealthTech ventures
Glacies Biome Luxembourg – glacies.bio/ | Transforming skincare by combining microbiome analysis, AI, and computer vision to deliver highly personalised diagnostics and optimised skincare regiment. |
Global Particle Therapy United States | Offering cancer patients access to affordable, advanced proton therapy. |
Helical Luxembourg – www.helical-ai.com/ | Open-core AI platform for pharma companies to accelerate & transform their drug discovery process. |
TrialCraft Belgium – trialcraft.health/ | AI-based medical writing tool that gives medical writers super-powers when drafting clinical study documentation. The underlying objective is to help patients, only faster. |
ZenZen Germany | 24/7 personalised support, meal planning, easy data tracking, and emotional assistance for pregnant women with diabetes. |
Space ventures
Aeon Luxembourg
| Bringing real-time centimeter-level GNSS positioning accuracy, offering an alternative or complimentary to real-time positioning services. |
Exobiosphere Luxembourg – exobiosphere.com/ | First space-based platform, designed to accelerate drug discovery by leveraging microgravity to deliver faster, more accurate biological insights. |
